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March 26, 2016
Table of Contents

1 Introduction
PLXNA2

Wikipedia

 

Plexin-A2 is a protein that in humans is encoded by the PLXNA2 gene.

This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.

In some studies, the PLXNA2 gene is associated with schizophrenia.







This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "PLXNA2".


Last Modified:   2010-11-25


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